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Case study confirms the high efficacy of an antimicrobial coating on adhesive films

September 2, 2021

“The results of the study show that antimicrobial-treated surfaces can make a valuable contribution to preventing the spread of multidrug-resistant pathogens in hospitals. Even daily surface disinfection cannot prevent recontamination in a matter of hours: antimicrobial surfaces can fill this gap. “

In a clinical study that lasted several months, the effectiveness of antimicrobial treated surfaces against hospital pathogens was examined under real conditions at the University Hospital basel in Switzerland. The research team, led by Prof. Dr. Andreas Widmer and Dr. R. Frei, confirmed that the adhesive film PURE ZONE® from HEXIS S.A.S. treated Sanitized® jointly developed has 98% efficacy against microbes.
The results were first published in the peer-reviewed scientific journal Antimicrobial Resistance & Infection Control. The study was supported by Innosuisse, the Swiss innovation agency.

A case study at the University Hospital Basel led by Professor Andreas Widmer and Dr. R. Frei addressed the question of whether and how effectively the antimicrobial adhesive film PURE ZONE® from HEXIS S.A.S. acts against the cause of what are commonly known as nosocomial infections (HAIs).
In this study, the adhesive film PURZON060B, commercially available from HEXIS S.A.S., was tested; a flexible and transparent product with an active ingredient based on silver ions provided by SANITIZED.

Study framework: frequently touched surfaces, with and without antimicrobial coating

A real situation was created by focusing the study on frequently touched surfaces in six patient rooms, three in the surgical department and three in the medical department. Specifically, bed tables, bedside tables, patient chair armrests, dining tables, toilet seats, and flush handles were included. The SANitized® treated PURZON060B film was applied to half of the surface, while the other half remained in its original state and served as a control surface.
During the study, which lasted several months, the patients’ rooms were cleaned normally once a day and the bathrooms were disinfected once a day. Samples of treated and untreated surfaces were taken twice a week on an area of 25 cm2 and subjected to an analysis of microorganisms. The number of microbes was determined by spreading on culture media, and isolates were examined for clinically relevant pathogens such as Staphylococcus aureus (including MRSA).

Long-term effect: A net and significant reduction in pathogens

A total of 403 samples were analysed. HEXIS S.A.S. SANITIZED®’s PURZON060B film led to a reduction in the total number of viable germs of 98.4% on the six different surface types. The largest reduction was measured on toilet seats and flush handles (99%). In addition, scientists have confirmed a very significant reduction in pathogens, especially enterococci. Their multidrug-resistant strains can survive on dry surfaces for up to four years and they were responsible for a nationwide outbreak in Swiss hospitals in 2017, which could only be contained after two years.
The long-term effect of the Sanitized® TREATED adhesive film PURZON060B from HEXIS S.A.S was confirmed by repeating the measurement after six months.

“A sustainable antimicrobial surface supports hygiene management in hospitals and healthcare facilities,” says Michael Lüthi, CEO of SANITIZED AG.

“The results of the study show that antimicrobial-treated surfaces can make a valuable contribution to preventing the spread of multidrug-resistant pathogens in hospitals. Even daily surface disinfection cannot prevent recontamination in a matter of hours: antimicrobial surfaces can fill this gap. ” explains Prof. Dr. Andreas Widmer.

“For our antimicrobial adhesive film PURE ZONE®, we cooperated with SANITIZED AG. Hospitals, residences for the elderly and care facilities benefit from decades of experience and the highest quality,” explains Clément Mateu, CEO of HEXIS S.A.S.